Preheat your oven to 400 degrees Fahrenheit. Place a wire rack over the top of a large rimmed baking sheet and set aside.
In a small bowl, mix together the honey, mustards, olive oil, lemon juice, and garlic. Season with salt and pepper and divide in half. Set aside one half for serving and dipping later.
Season the chicken with salt, pepper, and garlic powder. Prepare a bowl for the flour, a separate bowl with the other half of the honey mustard, and a separate bowl combining the panko and crushed pretzels.
Dredge the seasoned chicken breasts in the flour, shaking off the excess. Next, dip in the honey mustard, shaking off the excess. Finally, press the chicken into the mixture of the panko and pretzels then place on top of the prepared rack.
Bake in the preheated oven until golden brown, about 18-25 minutes, depending on the size of the chicken breasts. Serve fresh from the oven with the remaining honey mustard.
Serve fresh from the oven with the remaining honey mustard.